In vivo imaging of CT26 mouse tumours by using cmHsp70.1 monoclonal antibody
نویسندگان
چکیده
منابع مشابه
In vivo imaging of CT26 mouse tumours by using cmHsp70.1 monoclonal antibody
The major stress-inducible heat shock protein 70 (Hsp70) is frequently present on the cell surface of human tumours, but not on normal cells. Herein, the binding characteristics of the cmHsp70.1 mouse monoclonal antibody (mAb) were evaluated in vitro and in a syngeneic tumour mouse model. More than 50% of the CT26 mouse colon carcinoma cells express Hsp70 on their cell surface at 4°C. After a t...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2011
ISSN: 1582-1838
DOI: 10.1111/j.1582-4934.2010.01067.x